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    <title>ExAC Browser</title>
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        $(function() {
            var bestPictures = new Bloodhound({
              datumTokenizer: Bloodhound.tokenizers.obj.whitespace('value'),
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              remote: '/autocomplete/%QUERY'
            });

            bestPictures.initialize();

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    <div class="container">
        <div class="row">
            <div class="col-md-6">
                <h1><span class="hidden-xs">Variant: </span>1:66096104 AAG / A</h1>
                
            </div>
            <div class="col-md-6">
            
            </div>
        </div>
        <hr/>

        
            
                <p><span class="label label-warning">Warning!</span> This variant is only covered in 0 individuals (adjusted allele number = 0).<br/>
                This means that the site is covered in fewer than 80% of the individuals in ExAC, which may indicate a low-quality site.</p>
                <hr/>
            
            <div class="row">
                <div class="col-md-6">
                    <dl class="dl-horizontal" style="margin-bottom: 0px;">
                        <dt>
                            
                                <span class="label label-danger">Filter Status</span>
                            
                        </dt>
                        <dd>VQSRTrancheINDEL99.00to99.50</dd>
                        <dt>dbSNP</dt>
                        
                            <dd>Not found in dbSNP</dd>
                        
                        <dt>Allele Frequency</dt>
                        <dd>NA (Allele Number = 0)</dd>
                        <dt>Filtering AF</dt>
                        <dd data-tooltip="Filtering allele frequency (AF): a threshold for filtering variants that are too common to plausibly cause disease.
If the variant filtering AF is greater than the maximum credible population AF for the disease of interest, the variant
is too common to be causative and may be filtered. Click here to see the filtering AF calculator app and citation."><a target="_blank" href="http://cardiodb.org/allelefrequencyapp/">
                        0 (None)</a></dd>
                        <dt>Allele Count</dt>
                        <dd>0 / 0</dd>
                        <dt>UCSC</dt>
                        <dd>
                            <a href="http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg19&highlight=hg19.chr1%3A66096104-66096106&position=chr1%3A66096079-66096131" target="_blank">
                                1-66096104-AAG-A
                                <i class="fa fa-external-link"></i>
                            </a>
                        </dd>
                        <dt>ClinVar</dt>
                        <dd>
                            
                                <a href="http://www.ncbi.nlm.nih.gov/clinvar?term=(1%5BChromosome%5D)%20AND%2066096104%5BBase%20Position%20for%20Assembly%20GRCh37%5D" target="_blank">
                            
                                Click to search for variant in Clinvar
                                <i class="fa fa-external-link"></i>
                            </a>
                        </dd>
                    </dl>
                </div>
                <div class="col-md-6">
                    <div class="row">
                        <div class="col-md-8 col-md-offset-1">
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                                        <div class="panel-title">
                                            <a data-toggle="collapse" data-parent="#accordion" href="#gt_quality_collapse" aria-expanded="false" aria-controls="gt_quality_collapse">
                                                <small>Genotype Quality Metrics</small>
                                            </a>
                                        </div>
                                    </div>
                                    <div id="gt_quality_collapse" class="panel-collapse collapse" role="tabpanel" aria-labelledby="gt_quality_collapse_heading">
                                        <div class="row">
                                            <div class="col-md-10 col-md-offset-1">
                                                <div id="quality_metrics_container">
                                                    <span class="btn-group" data-toggle="buttons" id="quality_full_site_button_group">
                                                        <button class="btn btn-primary btn-sm active quality_full_site_buttons" id="variant_carriers_button"
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                                                            <input type="radio"> Variant carriers
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                                                        <button class="btn btn-primary btn-sm quality_full_site_buttons" id="variant_site_button"
                                                                data-tooltip="Show metric for all individuals (at this site, whether or not they have this allele).">
                                                            <input type="radio" > All individuals
                                                        </button>
                                                    </span>
                                                    <div id="quality_display_container" class="d3_graph"></div>
                                                    <small><span class="label label-info">Note:</span> Plot may include low-quality genotypes that were excluded from allele counts in the table above</small>
                                                    <span class="btn-group" data-toggle="buttons" id="quality_display_button_group" >
                                                        <button class="btn btn-primary btn-sm active quality_display_buttons" id="genotype_depths_button"
                                                                data-tooltip="Per sample depth. Capped at 100X">
                                                            <input type="radio"> Depth
                                                        </button>
                                                        <button class="btn btn-primary btn-sm quality_display_buttons" id="genotype_qualities_button"
                                                                data-tooltip="Per sample genotype quality.">
                                                            <input type="radio" > Genotype Quality
                                                        </button>
                                                    </span>
                                                </div>
                                                <br/>
                                            </div>
                                        </div>
                                    </div>
                                </div>
                                <div class="panel panel-default">
                                    <div class="panel-heading" role="tab" id="quality_collapse_heading"   style="height: auto">
                                        <div class="panel-title">
                                            <a data-toggle="collapse" data-parent="#accordion" href="#quality_collapse" aria-expanded="false" aria-controls="quality_collapse">
                                                <small>Site Quality Metrics</small>
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                                        </div>
                                    </div>
                                    <div id="quality_collapse" class="panel-collapse collapse" role="tabpanel" aria-labelledby="quality_collapse_heading">
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                                            <div class="col-md-10 col-md-offset-1">
                                                <div id="quality_metric_container"></div>
                                                <small><div id="site_quality_note"></div></small>
                                                <small><span class="label label-info">Note:</span> These are site-level quality metrics: they may be unpredictable for multi-allelic sites.</small>
                                                <select id="quality_metric_select" class="form-control">
                                                    <option><small>Site Quality: 652.42</small></option>
                                                    
                                                        <option><small>BaseQRankSum: 0.132</small></option>
                                                    
                                                        <option><small>MQRankSum: 0.849</small></option>
                                                    
                                                        <option><small>InbreedingCoeff: 0.2318</small></option>
                                                    
                                                        <option><small>VQSLOD: -1.765e-01</small></option>
                                                    
                                                        <option><small>FS: 12.081</small></option>
                                                    
                                                        <option><small>MQ: 53.35</small></option>
                                                    
                                                        <option><small>DP: 3723</small></option>
                                                    
                                                        <option><small>QD: 2.65</small></option>
                                                    
                                                        <option><small>ClippingRankSum: -7.950e-01</small></option>
                                                    
                                                        <option><small>ReadPosRankSum: 0.184</small></option>
                                                    
                                                </select>
                                                <br/>
                                            </div>
                                        </div>
                                    </div>
                                </div>
                            </div>
                        </div>
                    </div>
                </div>
            </div>
            <hr/>
        


        <div class="row">
            <div class="col-md-6">
                <div id="annotation_container">
                
                    <div class="section_header">Annotations</div>
                    
                        <p>This variant falls on 6 transcripts in 1 genes:</p>
                        <div class="panel-group" id="annotation_accordion" style="margin-bottom: 0px;">
                            <div class="row">
                                
                                    <div class="col-md-6" style="border-right: 1px dashed #AAA;">
                                
                                
                                    <span class="h4">3&#39; UTR</span>
<span style='float: right;'>

</span>
<ul>
    
        <li>
            <a href="/gene/ENSG00000116678">
            
                LEPR
            
            </a>
            
                
                 - <a href="/transcript/ENST00000371059">
                    ENST00000371059
                    
                </a>
                
            
        </li>
    
</ul>
                                
                                </div>
                                <div class="col-md-6">
                                
                                    <span class="h4">intron</span>
<span style='float: right;'>

</span>
<ul>
    
        <li>
            <a href="/gene/ENSG00000116678">
            
                LEPR
            
            </a>
            
                <span class="dropdown">
                    <button class="btn btn-default dropdown-toggle" type="button" id="transcript_dropdown" data-toggle="dropdown">
                        Transcripts
                        <span class="caret"></span>
                    </button>
                    <ul class="dropdown-menu" role="menu" aria-labelledby="transcript_dropdown">
                        
                            <li role="presentation">
                                <a role="menuitem" tabindex="-1" href="/transcript/ENST00000349533">
                                    ENST00000349533
                                    
                                        *
                                    
                                    
                                </a>
                            </li>
                        
                            <li role="presentation">
                                <a role="menuitem" tabindex="-1" href="/transcript/ENST00000371060">
                                    ENST00000371060
                                    
                                    
                                </a>
                            </li>
                        
                            <li role="presentation">
                                <a role="menuitem" tabindex="-1" href="/transcript/ENST00000406510">
                                    ENST00000406510
                                    
                                    
                                </a>
                            </li>
                        
                    </ul>
                </span>
            
        </li>
    
</ul>
                                
                                </div>
                            </div>
                        </div>
                        <small><span class="label label-info">Note:</span> This list may not include additional transcripts in the same gene that the variant does not overlap.</small>
                    
                
                </div>
                <div id="browser_container">
                </div>
            </div>

            <div class="col-md-6">
                
                    <div id="frequency_info_container">
                        <div class="section_header">Population Frequencies</div>
                        <div id="frequency_table_container" class="frequency_displays">
                            
                            <table id="frequency_table">
                                <thead>
                                    <tr>
                                        <th>Population</th>
                                        <th>Allele Count</th>
                                        <th>Allele Number</th>
                                        
                                            <th>Number of Homozygotes</th>
                                        
                                        
                                        <th>Allele Frequency</th>
                                    </tr>
                                </thead>
                                <tbody>
                                    
                                        <tr>
                                            <td>European (Non-Finnish)</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>East Asian</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>Other</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>African</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>Latino</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>South Asian</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                        <tr>
                                            <td>European (Finnish)</td>
                                            <td>0</td>
                                            <td>0</td>
                                            
                                                <td>0</td>
                                            
                                            
                                            
                                                <td>NA</td>
                                            
                                        </tr>
                                    
                                </tbody>
                                <tfoot>
                                    <tr>
                                        <td><b>Total</b></td>
                                        <td><b>0</b></td>
                                        <td><b>0</b></td>
                                        
                                            <td><b>0</b></td>
                                        
                                        
                                        <td><b>
                                            
                                                NA
                                            
                                        </b></td>
                                    </tr>
                                </tfoot>
                            </table>
                            
                        </div>
                    </div>
                
            </div>
        </div>

        
        </div>



</body>